Having read all the debate about what to highlight, I think there are a few practical points.
Firstly, the 5 to highlight are not known by the term 'Five'. So the first trap to avoid is going for the better known 'Five'. There are two 'Fives' in the title because there are two sets to consider, not two sets to highlight.
Secondly, the setter was limited in the number of letters in the message by the number of clues. KevGar was more or less forced to use 'more' instead of 'rather'.
Thirdly, the central cell resolves which set to highlight, since it could belong to both. Choosing one option excludes the other option.
Fourthly - and this is stretching it a bit - the triple-letter cell bottom right (which otherwise seems unconnected to the theme) with two adjoining cells is an anagram of the central cell's given name.
Finally, I have noticed that, when there has been debate in previous puzzles about what to highlight, the published solution tends to be the most straightforward of the solutions mooted.
But then again, I may be completely wrong. Time will tell.