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11d. Setting great store by a spot of publicity
HOARDING

2a. Brother to uncle Remus
BRER

4a. Devon town not quite right, one wanting money
CREDITOR

Parses for the above please.

HOARDING is another word for an advertising billboard
Uncle Remus's stories about Brer Rabbit, Brer Fox, etc. - BRER meant brother
CREDITO(n) +R

Thanks for this ChrisE.

12a. Search to be excluded from legacy
QUEST

21d. Wakes to one side
ASKEW

Parses for the above please.

12 (be)quest
21 anagram, but no anagram indicator!

Thanks chrisE.
21....yes , there's no indicator which is strange.

14a. Centrepoint of Grand Act demonstrates it
MIDDLE-C

20a. Relatives making ends meet with it
AKIN

28a. Stingy young women given 50s? Not quite
NEAR MISSES

Parses for the above please.

14a. refers to the centre key of a grand piano being middle C (not strictly true!) and “act” visually has C at the centre

20a. (m) akin (g)

28a. stingy - near
young women - misses

def. not quite

given 50's. ? what is clue number 50 ?