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Thanks again ChrisE

...and Jono too.

3d. Fiddle around in piece of Gothic fiction
REBECCA

12a. Penned by novelist, put out fake safety guide
GREEN CROSS CODE

1a. Item of tableware in broken state quietly put back
PLACE MAT

Parses for the above please.

3 D. A rebec is an old fiddle, musical instrument and Ca is circa, a out. Rebecca is the famous Du Maurier novel

12a. The novelist in GREENE (I assume Graham), put out is CROSS and fake is COD (definition 4 in Chambers).

1a. is a reversal of TAME (broken, as a horse), CAL (state), P (quietly, though softly is more accurate)

Thanks jono & malone, appreciated.

9a. Busy period requires routine with no time off, hospitals admitted.
RUSH HOUR

16d. Letting down front, crease fabric and squeeze once
OLD FLAME

19d. He died, supported by Duke in real push forward
OBTRUDE

21d. Nut enters rising river - that's devotion for you
NOVENA

16 FOLD LAME (crease fabric - there's an accent on the E of LAME) with the F moved down. "Squeeze" is a rather dated term for a girlfriend.

19 OB(it) died, then D in TRUE

21 I can see the river AVON, but en puzzles me

Nut is print room slang for the EN-dash.
Mutton is similar slang for EM.