Hi
Not sure about 'orientation'. The preamble is opaque, to say the least, and I'm really not sure which of the "clues to numbered answers, one of which..." is being referred to (it's also ambiguous, is it a clue or the answer to a clue?).
So, I simply filled the grid as presented, without rotating, reversing or mirroring.
If I had to say what the orientation is, it would be 'towards the centre'.