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8a Ploy contrived by Dr. No that eliminates the competition (8)

I have no crossers (solved 4 clues in total)

I tried making an anagram of PLOY + DRNO, to no avail.

Could someone please give me a hint?

Try a different abbreviation for Dr.
(I did what you did first too!)

Thank you. I got there with about my 4th go!