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Stuck on last three in top left corner:

1D Tree, thespian, originally playing in drama (8).
-A-----D
10A Pan West Coast city after increase is withdrawn (6)
---L-A
12A Potentially 22, English sporting venue (7). ---T-ES

Any ideas?

10. Paella . It's 'leap' backwards ('withdrawn') and LA/Los Angeles, West Coast city.

1d TAMARIND

Is there a clue 22 and do you have the answer to it? That might make 12 A bit easier.

Yes, sorry Malone, I should have put that in:
22D What can help you see wine's not sweet to begin with. (retina)

1 Think 12 A is Aintree, sporting venue. It's an anagram of 'retina'+ 'e'.

... the 'e' being from E(nglish).

Yes, of course. Thanks, Malone, for your help.

You're welcome.