do you mean the r? If my other answer for
Aloofness not seen in terraced house
answer: Detached retina? that is the R
I usually finish this eventually, first time for ages been stuck!
Apologies , did mean r. Human - being, ahead of "interest" - business claim makes me think that "human interest" - emotional content looks OK.
What letters do you have for "Aloofness not seen in terraced house". I don't have the crossword.