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Clue is:
1. Cavity inside bones in usage (5)
S- - - S

2. Clue is:
Muslim official at home once more. (5)
I - A - -

I though imam for no 2 but what for the last letter?

Thanks for any thoughts!

1 sinus, it's written within.

2, looks like again?

2. Are you sure about the I
Again, Aga + in?

Thanks hinge and trevor.

I reworked the clue that made me think it was an I. Now I see that again fits, and thanks for solving sinus. Clever people!