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last two:
51.Drink is seen around select feature of castle
54. Doctors depart with leading optometrist to identify spreader of disease.

Please help before I go mad!

51.Drink is seen around select feature of castle

port-cull-is

54. mosquito (MOs quit o)

54 abbreviation for doctors + word meaning to leave plus one letter [name of a disease spreader and also a WWII aircraft]

Thank you greedykite, escher and ixion. This is my first attempt at the quiz and I've got answers to all the clues even though I think I've got too many starting with P/Q. However I'll send it in and then study the answers when I get it back and hopefully that will help in future.