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Chemical in bodily tissue, not one in very old person (4) C?AL
Answer and wordplay appreciated

CHAL is an old word for a person.

Chemical is probably H but I can't see CAL.

Chalone is a chemical found in bodily tissue ('Tis in Chambers) so if you delete the' one' from Chalone you get One. Any ideas for 5 across
For model good health is the answer - I have P***IT

Sorry,y ou get CHAL not ONe.

PROSIT

prosit?

Thanks film fan

Yup, PRO (for) and SIT (model) gives Prosit, which means good health as in a toast.