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1A Pairs of pants, not individually wrapped, can't be dirty (10)
10A Small close by house is lighter option for drinking (10)
21A Sparkling urban hosts in agreement (10)
25A Cissy regularly finds space again outside revolving tower (10)

Compiler Donk.

21 C on form ity.

10, S handy gaff.

1a, Stainproof.

25, Sk ysc raper.

You're a lifesaver Rusty!

Glad to help, Aleck!