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10a.11lets.??d???r?o??.Toiling hard in Brazilian location,American breathes in powdery stuff.
17a.3words.6.2.6.?e???s ?f ?i?d?m.As something worth listening to,poems words fail miserably.

10A toiling hard (def) adj.
IN + DUST + RIO + US

17A anagram of POEM'S WORDS FAIL

PEARLS OF WISDOM

Good morning, ron.
10ac. Synonym of "hard-working", - in +"powdery stuff" (4) + "Brazilian city" (3) + "abbreviation for American" (1.1)
17ac. anagram of "poem's words fail" - 1st word can be cast before swine + of + think Norman!
Hoping this helps!
Al Issner

Thankyou all for help.