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33 down Character change for Doctor Who is concerning teenagers (12) ---e-e-a-i-n
35 across Perhaps a girlfriend's taken in easily at first by a cosmetic substance (4, 4) -l-e ---a
46 down Lamb perhaps made use of a book gathering for an audience (3, 4) r-d -e-t

red meat (sounds like, read meet).

33d regeneration (have to have watched Dr. Who)

aloe vera?

Thank you trevor

easily at first = E
E taken in by, A Lover, etc...

46 ....red meat

Thank you choosytoo. RED MEAT it is.