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21ac.)No longer afflicted with an infection. (4)
-MIT
I just can't see it-have I gone wrong elsewhere?

smit (old word for smitten?)

ta,scarlet

Found this by googling - the Scot and northern English dialect an infection he's got the smit.
I have a different letter missing though.
25A Jokingly confirm sacking opposite is a blunder (4) -ISH

Any help appreciated

BISH(op)