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Genus Coryphantha
- mainly globose cacti of southwestern United States and Mexico covered with many nodules; superficially resembling and formerly included in genus Mammillaria
Genus Echinocactus
- globular or cylindrical cacti; southwestern United States to Brazil
Genus Echinocereus
- large genus of low-growing shrubby ribbed cacti of Mexico and southwestern United States
Genus Epiphyllum
- small genus of tropical American (mainly Central America) cacti
Genus Ferocactus
- genus of nearly globular cacti of Mexico and southwestern United States: barrel cacti
Genus Gymnocalycium
- large genus of low-growing globular South American cacti with spiny ribs covered with many tubercles
Genus Harrisia
- genus of slender often treelike spiny cacti with solitary showy nocturnal white or pink flowers; Florida and Caribbean to South America
Genus Hatiora
- small genus of South American epiphytic or lithophytic cacti
Genus Hylocereus
- genus of climbing or epiphytic tropical American cacti with angular stems and mostly white very fragrant flowers
Genus Lemaireocereus
- tropical American cacti usually tall and branching with stout spines and funnel-shaped flowers and globular or ovoid often edible fruit