Below are possible answers for the crossword clue Thumb one's nose at.
4 letter answer(s) to thumb one's nose at
DEFY
challenge; "I dare you!"
elude, especially in a baffling way; "This behavior defies explanation"
resist or confront with resistance; "The politician defied public opinion"; "The new material withstands even the greatest wear and tear"; "The bridge held"
To go against
7 letter answer(s) to thumb one's nose at
DISDAIN
a communication that indicates lack of respect by patronizing the recipient
lack of respect accompanied by a feeling of intense dislike; "he was held in contempt"; "the despite in which outsiders were held is legendary"
look down on with disdain; "He despises the people he has to work for"; "The professor scorns the students who don't catch on immediately"
reject with contempt; "She spurned his advances"
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