Amos, I'm not sure which context of final answer. So I'll cover them both.
2D refers to "the final answer" : this is the answer to the last clue, 35D, which is ANE.
Also, there is the 'Final Answer' to be completed beneath the grid. If you've otherwise completed the puzzle, then you'll know that all the emotions extracted from answers have been re-utilised, two at a time, in the unclued entries. All but two, that is. So those two remaining extracted emotions should be anagrammed together to make a real word and this entered below the grid. I think that there is only one possible solution. Sometimes the word is associated with a cushion.