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Binks, you have col 1 wrongly aligned. I made the same mistake....

I have all the words and yes, Bradfords was perfect! I have 26 letters and the keyword I assume. Hints on how they might 'provide the them'. I have put them in various orders but, like Dottie, I'm just not getting it....

Kerching. I got it!

Thanks rrobbo for pointing out where I was going wrong in column 1. The clashes and gaps sorted themselves out after that although a couple of clues I'm unsure of.
The waitress in 10d. I've found ..PPY in other online dictionaries but not my 1988 Chambers. Can't see it spelt ..PPIE anywhere. Have I got that wrong? Gives me a scientific unclued 3-letter answer in row 6.
I'm sure I have the right injection on Col1 - nice trap Pointer set there with the first two letters of that column - but why must it cause amusement? Is that schoolboy humour or am I missing a subtle bit of wordplay? That injection almost sounds like a TLA if you say it - another bit of cleverness by Pointer?
Thanks everyone for the hints.

Jumble MUST with your answer to get?
Both spellings of the waitress given in current Chambers

Thanks Gem 94 - Google (which is pretty much everything ever) has no reference to that spelling. I've been happie with my old faithful slightly scrappie 88 Chambers, but now it's getting a bit crappie for solving the Listener. Shame there's no Kindle edition.

Also, was I the only one whose first word revealed by the substitution was in Col 2 and was fooled (again)? Aah, that's the first word of a famous organisation known by a TLA so there's the link - wrong!

Yup. I'm in that gang binks 8-). Col1 thankfully gave it away though.