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Just one answer needed , and would be grateful for any help.

19d Strike adversely affected almost everyone in France (3,3)

I have ?I? O?T and assume answer is probably HIT OUT but not able to fully parse it!

HIT OUT = Strike, and TOUT is French for all/everyone but still something missing?

adversely affected - Hit
Almost everybody in France - (t)out

Many thanks mamya, trust me to miss the obvious!

You're welcome, we all do it.