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Stuck on a few this week!
2d Runs with awkward situation that's put off a lover of regularity(9) R?U?I???T

15a .....getting upset, say, with regressing 10(answer to 10 is GLAMOUR) (8) ?r?s?i?e

27A Love play I'm adapting for London venue (7) No letters!

18d A couple o days' fighting included in reference in TV show 3,5)
?E?D???F

Thanks for the help

18d Red dwarf

2d Routinist
R + anagram of 'situation' minus A

15 prestige

27 looks like Olympia

and the other may be PRESTIGE but that's a wild stab

27 olympia