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2d, 2words, 3.4. C?r ???b, Underwear lifted in search for terrorist weapons.
3d, M?n???u?????, Unladylike, this roaring? That could be the charge.
17a, R?????r?, Farmworker --- dashed brave soul --- catching cold.
18d, ????s?a, Girl has a tan after travelling.
22a, 5words, 2.3.4.3.2. A? ??? ?a?e ?a? B?, Each asset renewed, possibly depending on conditions.

2d car bomb - bra reversed inside comb
3d mans laughter
17a ranchero
18d natasha (anagram)
22a as the case may be

Thanks sudokulover for your help, just 12a to finish, 2words, ?o?l Difference.

GOAL

Got it sudokulover, goal