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Just coming back to try & complete the Xword as I still have some gaps!
42D persistence (8) ??N???T?
35D right, privilege (11) P?E?O?A?I?E
1D deeply distressing (9) T?A???T?
41A Way of singing ar higher pitch (8) ?A??????

Tenacity

Prerogative

Traumatic

Falsetto

Thanks mamya!
25A. Design & manufacture of clothing (7) C?O)????

Couture

Thanks again... I' m just not switched on today!

48A. Peacefully (6)

calmly