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I've possibly (probably) gone horribly wrong with these.
54a Era before 1980s stylist loses final twitch in face (5,3,5). I have t?m??/?e?/r?t?n.
46d Climber is after core of solid mineral in rock (7). o?i???e.
Can anyone help, please.

54 Times New Roman - it's a typeface.

olivine (although technically it's a mineral, rather than a rock) - VINE after centre of sOLId

Thanks Malone and ChrisE. Re: Times new roman, why?

The New RomanTICS:

http://en.wikipedia.org/wiki/New_Romanticism

I've now got RHINO for 53a What makes toenail hard regularly turns up - on one's nose.
Is this right and why?

I'm afraid I'm useless at explaining answers - glad someone else is doing that! I got the answer just from the letters I had and knowing that type could mean typeface.

every other letter backwards in the clue from the word hard

Yes, but it's tricky
toenail hard backwards is drahlianeot
Take every other letter
dRaHlIaNeOt

Thanks AndyC - I should have got the reference to New Romantics.