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26 Across Was one when it came to civil rights in the US . I have the letters -s-n-e- must be wrong somewhere ? 8 ACROSS Changed , Altered ,
letters -U-O-E- NOT ABLE TO FIND ANYTHING TO FIT IN Yet again must be wrong some where . If anyone has done this crossword , would like to hear your answers ? Many thanks in advance.

mutated?

Thanks Paul got an o in BALDERDASH

26a pioneer.
21d thesis.

Thank you MRW .Spelling THESIS wrong , should know better than starting crosswords late at night .