Stuck on these clues,any help appreciated. Thanks.
4 across- Disentangle second hint about condition(8)????????
17 across- Playwright's tale brought in call for encore(7)?O?????
25 across- River: mostly a word describing water transportation system(6)??????
1 down- Six linked to a crime after distribution of tainted blood(8)?I??????
14 down- University positive over some golf and lodging in St Andrews(9)???????N?
16 down- Denounce money paid to senior officials?(8)??????T?