45a Resistance blocking rise after membership fee set at lower level? (8)
I have SUB?R?U? pretty clearly SUBGROUP can't see where resistance kicks in..
34a One can start to unfasten wheels (4)
I have U?I? 99% sure it's UNIT but where do the wheels fit in?
50d Items for eating - perhaps they are to be clapped in (5) I have I?O?S Again 99% sure it's IRONS but can't reconcile first part of clue!
39a Chemist put concoction in front of major (6) L?E?I? - don't know this one!