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I'm worried about 1ac which reads
Reaction of medical pioneer held back by noted German(8)
B-C-L-S-
I thought immediately Backlash, but it has 'back' in the clue which would be odd.I was then thinking along the lines of noted German making it end in LIST(z)but the medical pioneer is a mystery. Any thoughts or am I looking too deepl?

Bac salk< h

Just to explain- (Jonas) SALK in BACH (noted!
composer)

Thanks Tony